| Date | Time | Location | Visitor | Home | Result (Record) |
|---|---|---|---|---|---|
| Mar 4/22 7:30pm | 7:30pm | *Baytown Lee | VAR - Friendswood 3 | Baytown Lee 0 | W (1 - 0) |
| Mar 11/22 7:30pm | 7:30pm | *Baytown Sterling | VAR - Friendswood 7 | Baytown Sterling 0 | W (2 - 0) |
| Mar 2/22 5:30pm | 5:30pm | Challenger Stadium | VAR - Friendswood 1 | Clear Lake 0 | W (3 - 0) |
| Jan 6/22 12:00pm | 12:00pm | College Station HS (Tournament) | VAR - Friendswood 3 | College Station 0 | W (4 - 0) |
| Jan 18/22 7:30pm | 7:30pm | *Galveston Ball (Spoor Field) | VAR - Friendswood 8 | Galveston Ball 0 | W (5 - 0) |
| Feb 22/22 7:30pm | 7:30pm | *Goose Creek Memorial | VAR - Friendswood 2 | Goose Creek Memorial 0 | W (6 - 0) |
| Jan 25/22 7:30pm | 7:30pm | *LaPorte | VAR - Friendswood 5 | LaPorte 0 | W (7 - 0) |
| Jan 15/22 11:00am | 11:00am | Bryan HS (Bryan Tournament) | VAR - Friendswood 1 | Lake Creek 0 | W (8 - 0) |
| Jan 14/22 1:00pm | 1:00pm | Bryan HS (Bryan Tournament) | VAR - Friendswood 8 | Lindale 0 | W (9 - 0) |
| Apr 9/22 11:00am | 11:00am | **Turner Stadium (Regional Final Playoff) | VAR - Friendswood 0 | Magnolia 1 | L (9 - 1) |
| Feb 7/22 7:30pm | 7:30pm | *Manvel | VAR - Friendswood 4 | Manvel 0 | W (10 - 1) |
| Jan 13/22 3:00pm | 3:00pm | Rudder HS (Bryan Tournament) | VAR - Friendswood 3 | Pflugerville 0 | W (11 - 1) |
| Apr 8/22 1:00pm | 1:00pm | **Turner Stadium (Regional Semifinal Playoff) | VAR - Friendswood 3 | Pflugerville Hendrickson 2 | W (12 - 1) |
| Jan 7/22 6:00pm | 6:00pm | College Station HS (Tournament) | VAR - Friendswood 1 | Rock Hill 2 | L (12 - 2) |
| Feb 11/22 7:30pm | 7:30pm | *Santa Fe | VAR - Friendswood 3 | Santa Fe 0 | W (13 - 2) |
| Jan 8/22 10:00am | 10:00am | College Station HS (Tournament) | VAR - Friendswood 6 | Temple 0 | W (14 - 2) |
| Mar 18/22 7:30pm | 7:30pm | *Texas City | VAR - Friendswood 8 | Texas City 0 | W (15 - 2) |
| Jan 21/22 7:30pm | 7:30pm | *Friendswood | Goose Creek Memorial 0 | VAR - Friendswood 3 | W (16 - 2) |
| Feb 1/22 7:30pm | 7:30pm | *Friendswood | Baytown Lee 0 | VAR - Friendswood 7 | W (17 - 2) |
| Feb 8/22 7:30pm | 7:30pm | *Friendswood | Baytown Sterling 0 | VAR - Friendswood 7 | W (18 - 2) |
| Feb 16/22 7:30pm | 7:30pm | *Friendswood | Texas City 0 | VAR - Friendswood 9 | W (19 - 2) |
| Feb 19/22 12:00pm | 12:00pm | *Friendswood | Galveston Ball 0 | VAR - Friendswood 1 | W (20 - 2) |
| Feb 25/22 7:30pm | 7:30pm | *Friendswood | LaPorte 0 | VAR - Friendswood 9 | W (21 - 2) |
| Mar 8/22 7:30pm | 7:30pm | *Friendswood | Manvel 0 | VAR - Friendswood 2 | W (22 - 2) |
| Mar 15/22 7:30pm | 7:30pm | *Friendswood | Santa Fe 0 | VAR - Friendswood 3 | W (23 - 2) |
| Mar 24/22 7:00pm | 7:00pm | **Baytown Sterling (Bidistrict Playoff) | Nederland 0 | VAR - Friendswood 6 | W (24 - 2) |
| Mar 29/22 7:00pm | 7:00pm | **Stafford (Area Playoff) | Fulshear 0 | VAR - Friendswood 3 | W (25 - 2) |
| Mar 31/22 7:00pm | 7:00pm | **Alvin (Regional Quarterfinal Playoff) | Manvel 0 | VAR - Friendswood 4 | W (26 - 2) |
= Stats have been entered for this game
Notes:
*Denotes District Games
** Denotes Playoff Games
March 24 - 26 Bidistrict Playoffs
March 28 - 29 Area Playoffs
March 31 - April 2 Regional Quarterfinals
April 8 - 9 Regional Tournament
April 13 - 16 State Tournament
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