| # | Name | POS | B | T | H | W | School |
| 13 | Edgardo Alfonzo | 3B | R | R | 5'11" | 210 | -- |
| 16 | Garrett Anderson | LF | L | L | 6'3" | 225 | -- |
| 73 | Alberto Callaspo | INF | S | R | 5'10" | 175 | -- |
| 40 | Bartolo Colon | RHP | R | R | 5'11" | 250 | -- |
| 53 | Brendan Donnelly | RHP | R | R | 6'3" | 240 | Mesa Junior College |
| 60 | Scott Dunn | RHP | R | R | 6'3" | 200 | Texas |
| 17 | Darin Erstad | CF | L | L | 6'2" | 215 | Nebraska |
| 45 | Kelvim Escobar | RHP | R | R | 6'1" | 230 | -- |
| 9 | Chone Figgins | Utility | S | R | 5'7" | 180 | -- |
| 36 | Nick Gorneault | OF | R | R | 6'3" | 220 | Massachussetts |
| 63 | Kevin Gregg | RHP | R | R | 6'6" | 235 | -- |
| 27 | Vladimir Guerrero | RF | R | R | 6'3" | 225 | -- |
| 6 | Maicer Izturis | INF | S | R | 5'8" | 150 | -- |
| 37 | Greg Jones | RHP | R | R | 6'2" | 195 | Pasco-Hernando |
| 47 | Howie Kendrick | INF | R | R | 5'10" | 195 | St. John's River |
| 2 | Adam Kennedy | 2B | L | R | 6'1" | 185 | Cal State Northridge |
| 35 | Casey Kotchman | 1B | L | L | 6'3" | 215 | -- |
| 41 | John Lackey | RHP | R | R | 6'6" | 235 | Grayson County Junior College |
| 44 | Jeff Mathis | C | R | R | 6'0" | 180 | -- |
| 23 | Dallas McPherson | 3B | L | R | 6'4" | 230 | The Citadel |
| 28 | Jose Molina | C | R | R | 6'2" | 220 | Ladislao Martinez |
| 22 | Kendry Morales | INF | S | R | 6'1" | 220 | -- |
| 65 | Tommy Murphy | OF | S | R | 6'0" | 185 | Florida Atlantic |
| 86 | Mike Napoli | C | R | R | 6'0" | 205 | -- |
| 39 | Robb Quinlan | 1B-3B | R | R | 6'1" | 200 | Minnesota |
| 20 | Juan Rivera | OF | R | R | 6'2" | 205 | -- |
| 57 | Francisco Rodriguez | RHP | R | R | 6'0" | 180 | -- |
| 33 | J.C. Romero | LHP | S | L | 5'11" | 205 | Mobile |
| 54 | Ervin Santana | RHP | R | R | 6'2" | 160 | -- |
| 64 | Joe Saunders | LHP | L | L | 6'3" | 210 | Virginia Tech |
| 62 | Scot Sheilds | RHP | R | R | 6'1" | 170 | Lincoln Memorial |
| 84 | Steven Shell | RHP | R | R | 6'5" | 190 | -- |
| Jeff Weaver | RHP | R | R | 6'5" | 200 | Fresno State | |
| 77 | Reggie Willits | OF | S | R | 5'11" | 185 | Oklahoma |
| 59 | Esteban Yan | RHP | R | R | 6'4" | 255 | -- |
| # | Name | POS |
| 14 | Mike Scoscia | Manager |
| 24 | Bud Black | Pitching Coach |
| 7 | Mickey Hatcher | Hitting Coach |
| 4 | Alfredo Griffin | First Base Coach |
| Dino Ebel | Third Base Coach | |
| 10 | Ron Roenicke | Bench Coach |
| 48 | Orlando Mercado | Bullpen Coach |
| 12 | Steve Soliz | Bullpen Catcher |